4C Research Group
CognitionConsciousnessCritical Care
We study brain health in critically ill children—combining neuroimaging, bedside monitoring, and multicenter collaboration to improve outcomes.
Self-paced learning modules and quizzes on PICU neuro topics—open to everyone, with optional sign-in to save your progress.
Knowledge MobilizationInterested in partnering? We work with clinicians, hospitals, and industry on studies from neuroprognostication to ICU delirium and quantitative EEG.
Our Mission
We are dedicated to advancing the understanding and treatment of cognitive and consciousness disorders in critically ill children. Our multidisciplinary team combines expertise in pediatric critical care, neuroscience, and biomedical engineering to develop innovative solutions that improve patient outcomes.
Through cutting-edge research and clinical collaboration, we strive to make a meaningful difference in the lives of children and their families.

Collaborative Research Excellence
Bringing together diverse expertise to transform pediatric care
Gallery
Moments from our lab — research, collaboration, and breakthroughs.







Our Impact
Driving innovation in pediatric critical care through dedicated research and collaboration
Research Themes
Exploring the frontiers of neuroprognostication and brain monitoring in critical care
Neuroprognostication
Predicting outcomes in acquired brain injury
- PREDICT ABI
- Common Data Elements
- GERMINAL Project
ICU Delirium & Sleep
Tracking brain connectivity in at-risk children
- TraNSIENCE
- BrainCASH
- Sleep Deprivation Studies
EEG Monitoring
Quantitative EEG for enhanced neuromonitoring
- NuANCEd
- qEEG Metrics
- Machine Learning Framework
Pain & Comfort
Advancing outcomes in pediatric critical care
- ABOVE Trial
- In-SYNCC Survey
- Multi-center Studies
Latest Research News
Researchers investigate a new method of sedation for paediatric patients
Scientists at Children’s Health Research Institute (a program of Lawson Health Research Institute), Sunnybrook Research Institute and The Hospital for Sick Children (SickKids) are working together to study the potential benefits of inhaled sedation as an alternative to keep critically ill children sedated and comfortable.
Read the full article on SickKids
Stay updated with the latest breakthroughs in pediatric critical care research
Featured Projects
Highlighting our funded research initiatives and collaborations

NuANCEd
Nurse-led Advanced Neuromonitoring in Critically ill children with Encephalopathy

TraNSIEnCe
Tracking Neurocognitive States In Encephalopathic Critically ill children

PREDICT ABI
Predicting outcomes in critically ill children with acquired brain injury
Join Our Research Community
We are always looking for passionate researchers, students, and collaborators to join us in advancing the frontiers of cognitive science and critical care research.
Stay Connected
Follow Us on Social Media
Stay updated with our latest research findings, team updates, and insights into pediatric critical care. Follow us on social media to be part of our research community.
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