Pediatric neurocritical care research

4C Research Group

CognitionConsciousnessCritical Care

We study brain health in critically ill children—combining neuroimaging, bedside monitoring, and multicenter collaboration to improve outcomes.

Self-paced learning modules and quizzes on PICU neuro topics—open to everyone, with optional sign-in to save your progress.

Knowledge Mobilization

Interested in partnering? We work with clinicians, hospitals, and industry on studies from neuroprognostication to ICU delirium and quantitative EEG.

Our Mission

We are dedicated to advancing the understanding and treatment of cognitive and consciousness disorders in critically ill children. Our multidisciplinary team combines expertise in pediatric critical care, neuroscience, and biomedical engineering to develop innovative solutions that improve patient outcomes.

Through cutting-edge research and clinical collaboration, we strive to make a meaningful difference in the lives of children and their families.

Medical research team collaborating

Collaborative Research Excellence

Bringing together diverse expertise to transform pediatric care

Gallery

Moments from our lab — research, collaboration, and breakthroughs.

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Our Impact

Driving innovation in pediatric critical care through dedicated research and collaboration

12+
Research Projects
90+
Publications
10+
Team Members
5+
Institutions

Research Themes

Exploring the frontiers of neuroprognostication and brain monitoring in critical care

Neuroprognostication

Predicting outcomes in acquired brain injury

  • PREDICT ABI
  • Common Data Elements
  • GERMINAL Project

ICU Delirium & Sleep

Tracking brain connectivity in at-risk children

  • TraNSIENCE
  • BrainCASH
  • Sleep Deprivation Studies

EEG Monitoring

Quantitative EEG for enhanced neuromonitoring

  • NuANCEd
  • qEEG Metrics
  • Machine Learning Framework

Pain & Comfort

Advancing outcomes in pediatric critical care

  • ABOVE Trial
  • In-SYNCC Survey
  • Multi-center Studies

Latest Research News

Researchers investigate a new method of sedation for paediatric patients

Scientists at Children’s Health Research Institute (a program of Lawson Health Research Institute), Sunnybrook Research Institute and The Hospital for Sick Children (SickKids) are working together to study the potential benefits of inhaled sedation as an alternative to keep critically ill children sedated and comfortable.

Read the full article on SickKids
Medical research collaboration
Research News

Stay updated with the latest breakthroughs in pediatric critical care research

Featured Projects

Highlighting our funded research initiatives and collaborations

NuANCEd
Implementation Science
AMOSO Opportunities Fundactive

NuANCEd

Nurse-led Advanced Neuromonitoring in Critically ill children with Encephalopathy

2 members
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TraNSIEnCe
Clinical Research
Brain Canada Future Leaders in Brain Research Awardactive

TraNSIEnCe

Tracking Neurocognitive States In Encephalopathic Critically ill children

2 members
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PREDICT ABI
Clinical Research
AMOSO Innovation Fundupcoming

PREDICT ABI

Predicting outcomes in critically ill children with acquired brain injury

2 members
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Join Our Research Community

We are always looking for passionate researchers, students, and collaborators to join us in advancing the frontiers of cognitive science and critical care research.

Stay Connected

Follow Us on Social Media

Stay updated with our latest research findings, team updates, and insights into pediatric critical care. Follow us on social media to be part of our research community.

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