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Clinical Research
activeTraNSIEnCe
Tracking Neurocognitive States In Encephalopathic Critically ill children
2023 – 20262 team members

Overview
This study aims to characterize functional and effective brain connectivity in critically ill children at varying degrees of risk for delirium. As part of this study, we enroll critically ill children at low-risk and high-risk for PICU delirium. We track their neurocognitive state using clinical behavioral scores, electroencephalography (EEG) and optical neuroimaging (fNIRS) techniques to identify objective predictors and signatures of delirium in critically ill children.
Objectives
- Characterize brain connectivity patterns in children at risk for PICU delirium
- Identify objective neurophysiological markers of delirium
- Develop early detection methods using EEG and fNIRS
- Improve understanding of delirium pathophysiology in critically ill children
Team members
Dr. Ganesan
Principal Investigator
LHSC Team
Clinical Partners
Project details
- Category
- Clinical Research
- Status
- active
- Start date
- 5/14/2023
- End date
- 6/29/2026
- Funding
- Brain Canada Future Leaders in Brain Research Award
Tags
Brain ConnectivityDeliriumPediatric Critical CareEEGfNIRSNeuroimaging
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